Nitroxide Radical-Containing Redox Nanoparticles Protect Neuroblastoma SH-SY5Y Cells against 6-Hydroxydopamine Toxicity

Figure 1

Structures of studied antioxidant compounds: nitroxide radical-containing redox nanoparticles 1 (copolymer based on poly(styrene-co-malein anhydride; NRNP1) (a), free nitroxide radicals: 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) (b), 4-amino-2,2,6,6-tetramethylpiperidine-1-oxyl (4-amino-TEMPO) (c), pH-sensitive radical-containing nanoparticles (NRNP2) (d), and nitroxide radicals-containing redox nanoparticles 3 (a copolymer of sorbitan-fatty acid esters with 4-amino-TEMPO; NRNP3) (e).

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(b)

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