Research Article

Nitroxide Radical-Containing Redox Nanoparticles Protect Neuroblastoma SH-SY5Y Cells against 6-Hydroxydopamine Toxicity

Table 2

Reducing activity of the 6-hydroxydopamine, antioxidant amino acids, and standard antioxidants (ABTS assay) and generation of hydrogen peroxide in DMEM/F12 medium.

Compound.Fast ABTS scavenging activity (Mol TE/Mol)Slow ABTS scavenging activity (Mol TE/Mol)H2O2 (μM)

6-Hydroxydopamine7.8 ± 1.5
Tyrosine
Tryptophan
Ascorbic acid33.6 ± 0.9
Glutathionend

; (independent samples). and: not detectable amounts; TE: Trolox equivalents.