Curcumin Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behaviors via Restoring Changes in Oxidative Stress and the Activation of Nrf2 Signaling Pathway in Rats

Figure 6

Effect of CUR on synaptic plasticity. (b) pCREB/CREB ratio in the hippocampus, (c) protein expression of BDNF in the hippocampus, (d) protein expression of PSD-95 in the hippocampus, (e) protein expression of synaptophysin in the hippocampus, (f) representative images of dendritic spines from DG granule neurons in the rat, (g) spine density in different groups, (h) representative images of DG granule neurons in the rats, and (i) total dendritic length in different groups. Data are expressed as (). and compared to the control group. ^# and ^## compared to the CUMS group.

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