MicroRNA-874-3p Aggravates Doxorubicin-Induced Renal Podocyte Injury via Targeting Methionine Sulfoxide Reductase B3

Figure 3

MsrB3 is the target gene of miR-874-3p. (a) miR-874-3p levels in human podocytes, mouse primary podocytes, and mice based on real-time PCR assay. (b) The diagram of miR-874-3p conservative seed binding sites on the 3-UTRs of the target genes (MsrB3). (c) The results of the double luciferase reporter assay. (d, e) The expression levels of MsrB3 after cotransfection. All data are listed as the (). compared with control groups; compared with the NC group; ^# compared with the MsrB3 plasmid group; ns: no significance.

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