Oxidative Medicine and Cellular Longevity / 2020 / Article / Fig 4

Research Article

ZNRD1 and Its Antisense Long Noncoding RNA ZNRD1-AS1 Are Oppositely Regulated by Cold Atmospheric Plasma in Breast Cancer Cells

Figure 4

ZNRD1 but not ZNRD1-AS1 stimulates proliferation of MCF-7. (a) Either ZNRD1 or ZNRD1-AS1 was downregulated in MCF-7 using siRNA, and cell survival was examined by colony formation assay. Three independent experiments were performed, and representative images are shown. The effect of the siRNA-driven downregulation of ZNRD1 (b) or ZNRD1-AS1 (c) on cell proliferation was examined by CCK-8 assays. The experiments were performed independently at least three times, and the values are presented as the . siNC: control siRNA; siZNRD1: siRNA for ZNRD1; siZNRD1-AS1: siRNA for ZNRD1-AS1. , .

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