ZNRD1 and Its Antisense Long Noncoding RNA ZNRD1-AS1 Are Oppositely Regulated by Cold Atmospheric Plasma in Breast Cancer Cells
ZNRD1 but not ZNRD1-AS1 stimulates proliferation of MCF-7. (a) Either ZNRD1 or ZNRD1-AS1 was downregulated in MCF-7 using siRNA, and cell survival was examined by colony formation assay. Three independent experiments were performed, and representative images are shown. The effect of the siRNA-driven downregulation of ZNRD1 (b) or ZNRD1-AS1 (c) on cell proliferation was examined by CCK-8 assays. The experiments were performed independently at least three times, and the values are presented as the . siNC: control siRNA; siZNRD1: siRNA for ZNRD1; siZNRD1-AS1: siRNA for ZNRD1-AS1. ,.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.