Research Article
Transcriptomic Analysis Reveals the Protection of Astragaloside IV against Diabetic Nephropathy by Modulating Inflammation
Figure 3
Heatmap analysis of DEGs among the kidneys of different groups of rats. At the end of treatment, three kidney cortex tissues from each group of rats were obtained and their RNAs were extracted for RNA-seq. The DEGs in the kidney tissues were hierarchically clustered and presented as heatmaps. (a) The downregulated DEGs () in the AS-IV group. (b) The upregulated DEGs () in the AS-IV group. NC: normal group; DN: diabetic nephropathy model group; DN-AS-IV: AS-IV-treatment group. Here, 1 represents the highest expression while -1 the lowest expression.
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