Research Article
Metformin Promotes Axon Regeneration after Spinal Cord Injury through Inhibiting Oxidative Stress and Stabilizing Microtubule
Figure 3
Metformin treatment blocked SCI-triggered apoptosis via activating the PI3K/Akt pathway after SCI. (a, b) TUNEL staining in the sham, SCI, SCI+metformin, and SCI+metformin+LY294002 group. . (c) Representative western blots of cleaved caspase3 (C-caspase3), Bax, and Bcl-2 in each group. (d–f) Quantification of western blots data from (c). ; and vs. the indicated group.
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