Research Article
Metformin Promotes Axon Regeneration after Spinal Cord Injury through Inhibiting Oxidative Stress and Stabilizing Microtubule
Figure 6
Metformin increased the expression of antioxidant proteins by activating the Nrf2/ARE signaling pathway after SCI. (a) Representative western blots of Nrf2, HO-1, and NQO1 in each group. (b–d) Quantification of western blots data from (a). ; and vs. the indicated group. (e) Coimmunofluorescence images show HO-1 (green) and NeuN (red) after SCI in each group. . (f) Coimmunofluorescence images show NQO1 (green) and NeuN (red) after SCI in each group. .
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