Metformin Promotes Axon Regeneration after Spinal Cord Injury through Inhibiting Oxidative Stress and Stabilizing Microtubule

Figure 8

Metformin inhibited oxidative stress via activating the Akt/Nrf2/ARE signaling pathway. (a) Representative western blots of Nrf2-nuclear and Nrf2-cytosol in each group. (b) Quantification of western blots data from (a). vs. the indicated group. (c) Representative western blots of p-Akt and t-Akt in each group. (d) Quantification of western blots data from (c). and vs. the indicated group. (e) Representative western blots of HO-1 and NQO1 in each group. (f, g) Quantification of western blots data from (e). , , and vs. the indicated group.

(a)

(b)

(c)

(d)

(e)

(f)

(g)