Critical Evaluation of the Interaction of Reactive Oxygen and Nitrogen Species with Blood to Inform the Clinical Translation of Nonthermal Plasma Therapy

<div>Experimental design to determine the stability of persistent ROS/RNS. (a) The mode of action of Eu.1 for detecting ONOO− is shown. (b) PBS (blue), BP (yellow), and processed whole blood (red) were analyzed following direct and indirect NTP treatment. Following treatment, the sample was either analyzed immediately (0 s) or after a delay (between 30 and 300 s) for RNS, H2O2, or ONOO− (μs-DBD: microsecond-pulsed dielectric barrier discharge; λex: excitation wavelength; λem: emission wavelength).</div>

Oxidative Medicine and Cellular Longevity

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Figure 1: Critical Evaluation of the Interaction of Reactive Oxygen and Nitrogen Species with Blood to Inform the Clinical Translation of Nonthermal Plasma Therapy 

Figure 1 | Critical Evaluation of the Interaction of Reactive Oxygen and Nitrogen Species with Blood to Inform the Clinical Translation of Nonthermal Plasma Therapy 