Chloroquine Improves Deoxynivalenol-Induced Inflammatory Response and Intestinal Mucosal Damage in Piglets

Figure 2

Relative mRNA levels of genes (TNFα, IL-6, IL-8, IFN-γ, TGF-β1, IL-1α, IL-12, IL-4) related to cytokine in the jejunum (a, b) and ileum (c, d) of weanling piglets. The real-time PCR method was employed, and β-actin was used as an internal control. Dietary treatment: CON: saline solution; DON: deoxynivalenol diet and saline solution; RAPA+DON: rapamycin and deoxynivalenol diet; CQ+DON: chloroquine and deoxynivalenol diet. Data are expressed as (), four models chosen. ^a,b,cMean values with different letters were considered to be significantly different (). If “ab” is on top of the column the measurement is neither significant compared to “a” or “b”, the same of other.

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