|
| Study name | Reid | Linsenmeyer | Waites | Lee | Hess | Sappal |
| Year | 2001 | 2004 | 2004 | 2007 | 2008 | 2018 |
|
| Study design | Longitudinal | Crossover randomized controlled | Parallel randomized controlled | Parallel (4 groups) randomized controlled | Crossover randomized controlled | Parallel randomized controlled |
| Intervention Cranberry | Juice 750 mL (, mealtimes) PAC content not reported | Tablets 1.2 g/d () PAC content not reported | Capsule 2.0 g/d
PAC content not reported | Tablets 1.6 g/d CB 1.6 g/d + MH 0.2 g/d PAC content not reported | Tablet 1.0 g/d () PAC content not reported | Capsule
PAC content 36 mg |
| Control | Water 750 mL (, mealtimes) | Placebo | Placebo identical (lactose) | Placebo and MH 0.2 g/d | Placebo identical (rice flour) | Placebo |
| Study duration | 1 week each, 2 days washout | 4 weeks each, 1 week washout | 6 months | 6 months | 6 months | 15 days |
| Outcomes | Bacteriuria
Bacterial biofilm load | Bacteriuria, pyuria | Bacteriuria | Symptomatic UTI | Symptomatic UTI | Bacteriuria, pyuria |
| Bacteriuria (cut-off) | Not specified | Midstream specimen of urine: ≥104/mL catheter specimen of urine: >105/mL | Catheter specimen of urine: ≥104/mL | ≥105/mL | ≥104/mL | ≥105/mL |
| Reported effects | Water: 7/15
CB juice: 7/15 | Not significant | Treatment: 10/26 Control: 8/22 | Treatment (CB and CB+MH): 67/153
Control (placebo and MH): 71/152 | Treatment: 6/47
Control: 16/47 | Not significant |
| Adverse effects | Not reported | Not reported | Not reported | Mild and infrequent | Not reported | Not reported |
|
