Irisin Rescues Blood-Brain Barrier Permeability following Traumatic Brain Injury and Contributes to the Neuroprotection of Exercise in Traumatic Brain Injury

Figure 5

Effects of exogenous irisin on the inflammatory response at 24 h after TBI in mice. (a, c, e, g) Content of TNF-α, IL-1β, IL-4, and IL-10 in brain tissue at 24 h after TBI. (b, d, f, h) Content of TNF-α, IL-1β, IL-4, and IL-10 in serum at 24 h after TBI. Data are expressed as the . . Significance was determined by one-way ANOVA and Dunnett’s post hoc analysis. versus Sham group; ^# versus TBI group.

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