Ivabradine Ameliorates Cardiac Function in Heart Failure with Preserved and Reduced Ejection Fraction via Upregulation of miR-133a

Table 4

Heart rate, blood pressure, and echocardiography parameters in HFrEF mice.

	Sham	HFrEF	HFrEF+low IVA	HFrEF+high IVA
HR (beats per min)		^#	^#
DBP (mmHg)		^#	^#	^#
SBP (mmHg)		^#	^#	^#
IVSTd (mm)		^#	^#	^#
LVPWd (mm)		^#	^#	^#
LVIDd (mm)		^#	^#	^#
LVIDs (mm)		^#	^#	^#
IVRT (ms)		^#	^#
EDT (ms)		^#	^#
LVEF (%)		^#	^#
FS (%)		^#

Values are expressed as ( mice per group). ^#Compared with the sham group, . Compared with the HFrEF group, , one-way ANOVA with the Bonferroni posttest. HR: heart rate; DBP: diastolic blood pressure; SBP: systolic blood pressure; IVSTd: interventricular septal thickness at diastole; LVPWd: left ventricular posterior wall thickness at diastole; LVIDd: left ventricular internal diameter at end-diastole; LVIDs: left ventricular internal diameter at end-systole; IVRT: isovolumic relaxation time; EDT: E peak deceleration time; EF: left ventricular ejection fraction; FS: fractional shortening.