Saccharomyces boulardii Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Regulating NF-κB and Nrf2 Signaling Pathways

Figure 5

Inhibitory effect of S. boulardii on NF-κB signaling pathway in ulcerative colitis induced by DSS in mice. Relative expression of mRNA in the colon (a) Il1b, (b) Il6, (c) Tnf, and (d) Tgfb1. Representative western blot images (e) and quantification of (f) p-NF-κB p65, (g) NF-κB p65, (h) IκKα, and (i) IκKβ. (j) Immunofluorescence analysis of NF-κB p65 (red) in colon (Magnification: ×400; Scale bars: 20 μm). DAPI was used for nuclear counterstaining (blue). . Values are presented as . versus control group. , and compared with the other groups. Sb: S. boulardii.

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