Research Article
ALDH2/SIRT1 Contributes to Type 1 and Type 2 Diabetes-Induced Retinopathy through Depressing Oxidative Stress
Table 1
General characteristics of the included diabetic patients.
| | Characteristic | T1DM () | T2DM () | CON () | value |
| | Female (%) | 6(40.0%) | 28(50.9%) | 8(53.3%) | | | Age (years) | | ## | | 0.002 | | BMI (kg/m2) | | | | ns | | Duration of diabetes (years) | | ## | | 0.001 | | Systolic blood pressure (mmHg) | | | | ns | | Diastolic blood pressure (mmHg) | | | | ns | | HbA1c (%) | | | | <0.001 | | Fasting blood glucose (mmol/L) | | | | <0.001 | | Therapy components | | | | | | Diet only (%) | 0 | 0 | | | | Insulin (%) | 15(100%) | 51(92.7%) | | | | Sulfonylureas (%) | 0(0%) | 8(14.5%) | | | | α-Glucosidase inhibitors (%) | 11(73.3%) | 31(56.4%) | | | | Biguanides (%) | 9(60.0%) | 47 (85.5%) | | | | Retinal thickness (μm) | | | | ns | | ERG test | | | | | | Amplitude of max b (μv) | | ## | | 0.001 | | Amplitude of OPs2 (μv) | | | | <0.001 |
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The results are described as (SD) or number (%). ns: no significance. : T1DM cohort and T2DM cohort vs. CON cohort; ##: T2DM cohort vs. T1DM cohort. |
