Research Article
Jie-Yu-He-Huan Capsule Ameliorates Anxiety-Like Behaviours in Rats Exposed to Chronic Restraint Stress via the cAMP/PKA/CREB/BDNF Signalling Pathway
Figure 5
Treatment with Jie-Yu-He-Huan capsule prevents alterations in the 5-hydroxytryptamine (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) concentrations caused by chronic restraint stress. (a) 5-HT level in the prefrontal cortex (PFC). (b) 5-HIAA level in the PFC. (c) 5-HT/5-HIAA ratio in the PFC. (d) 5-HT level in the hippocampus. (e) 5-HIAA level in the hippocampus. (f) 5-HT/5-HIAA ratio in the hippocampus. compared to the control group, compared to the control group, and # compared to the model group (unpaired -test). Data are expressed as the . The small circles represent individual data points.
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