Research Article
HIF-1α Activation Promotes Luteolysis by Enhancing ROS Levels in the Corpus Luteum of Pseudopregnant Rats
Figure 9
Inhibition of autophagy attenuates PGF2α-induced ROS production and cell apoptosis. (a) Inhibition of autophagy attenuates ROS production in luteal cells. Cells were treated with PGF2α for 24 h with or without 3-MA. (b) Representative immunoblotting and (c) densitometric qualification for the effect of autophagy inhibition on caspase-3 activation. Cells were treated with PGF2α for 24 h with or without 3-MA. #, vs. PGF2α.
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