Research Article
The Preventive Effect of Cardiac Sympathetic Denervation Induced by 6-OHDA on Myocardial Ischemia–Reperfusion Injury: The Changes of lncRNA/circRNAs-miRNA-mRNA Network of the Upper Thoracic Spinal Cord in Rats
Figure 4
Differential expression patterns of lncRNAs, circRNAs, and mRNAs. (a) The specific lncRNAs, circRNAs, and mRNAs shared between IR group and SD-IR group. (b) The volcano plot of lncRNAs, circRNAs, and mRNAs expression. Red color is indicative of upregulated and blue color is indicative of downregulated genes, where p < 0.05 and |FC| > 2 are considered statistically significant; grey color is indicative of nonsignificantly different genes. (c) The hierarchical heat map shows the deregulated lncRNAs, circRNAs, and mRNAs in the T1–T4 spinal cord segments between IR group and SD-IR group; up- and downregulated genes are colored in red and green, respectively (p < 0.05 and log2|FC| > 1).
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