Research Article

The Preventive Effect of Cardiac Sympathetic Denervation Induced by 6-OHDA on Myocardial Ischemia–Reperfusion Injury: The Changes of lncRNA/circRNAs-miRNA-mRNA Network of the Upper Thoracic Spinal Cord in Rats

Table 3

The detail information of the top 30 down-regulated mRNAs in the T1-4 spinal cord between SD-IR group and IR group.

Gene IDlog2FC (SD-IR/IR)PvalueDescription

LOC100912599-5.310.010395NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial-like
LOC100911994-3.890.01095Coiled-coil domain-containing protein 132-like
Clcn2-3.510.029527Chloride channel, voltage-sensitive 2
LOC100910308-3.477.97E-05Multifunctional protein ADE2-like
LOC100910207-3.120.018014Protein Dr1-like
Vwa5a-2.620.02532von Willebrand factor A domain containing 5A
Dpep1-2.530.015698Dipeptidase 1 (renal)
NEWGENE_1582994-2.450.02675DCN1, defective in cullin neddylation 1, domain containing 2
LOC103689986-2.411.64E-06Protein YIF1B
Iqcf3-2.400.036362IQ motif containing F3
Ahsg-2.320.021173Alpha-2-HS-glycoprotein
Hpgd-2.010.008083Hydroxyprostaglandin dehydrogenase 15 (NAD)
RGD1561778-1.940.016898Similar to dendritic cell-derived immunoglobulin(Ig)-like receptor 1, DIgR1 - mouse
LOC297568-1.880.032025Alpha-1-inhibitor III
Rlim-1.780.042544Ring finger protein, LIM domain interacting
Slc39a12-1.650.017633Solute carrier family 39 member 12
LOC100911865-1.621.20E-02TBC1 domain family member 12-like
Myo18b-1.610.003815Myosin XVIIIb
Tspan10-1.590.012324Tetraspanin 10
Sds-1.570.025502Serine dehydratase
Trim63-1.390.010581Tripartite motif containing 63
LOC102550588-1.380.030436Zinc finger protein 709-like
Sh2d4b-1.372.44E-05SH2 domain containing 4B
Hif3a-1.350.002856Hypoxia inducible factor 3, alpha subunit
Galnt15-1.300.01374Polypeptide N-acetylgalactosaminyltransferase 15
LOC687780-1.300.029663Similar to Finkel-Biskis-Reilly murine sarcoma virusubiquitously expressed
Trpv4-1.290.015774Transient receptor potential cation channel, subfamily V, member 4
Mt1-1.180.033903Metallothionein 1
Fbxw10-1.110.016073F-box and WD repeat domain containing 10
Dcst1-1.100.024549DC-STAMP domain containing 1

; p < 0.05 by analysis of variance.