The Preventive Effect of Cardiac Sympathetic Denervation Induced by 6-OHDA on Myocardial Ischemia–Reperfusion Injury: The Changes of lncRNA/circRNAs-miRNA-mRNA Network of the Upper Thoracic Spinal Cord in Rats

Table 8

The Gene Ontology (GO) terms enriched for the differentially expressed genes.

GO ID	Term	Gene number	Pvalue
biological_process
GO:0035458	Cellular response to interferon-beta	12	1.80E-18
GO:0006952	Defense response	11	2.39E-14
GO:0071346	Cellular response to interferon-gamma	9	2.22E-08
GO:0071222	Cellular response to lipopolysaccharide	11	2.09E-07
GO:0050832	Defense response to fungus	4	8.84E-07
GO:0070098	Chemokine-mediated signaling pathway	6	9.17E-07
GO:0031640	Killing of cells of other organism	4	2.35E-06
GO:0032496	Response to lipopolysaccharide	12	2.41E-06
GO:0042742	Defense response to bacterium	8	2.62E-06
GO:0019731	Antibacterial humoral response	4	3.59E-06
cellular_component
GO:0005615	Extracellular space	34	8.43E-09
GO:0005623	Cell	6	4.24E-05
GO:0030863	Cortical cytoskeleton	3	0.00016
GO:0031012	Extracellular matrix	8	0.000245
GO:0000786	Nucleosome	4	0.000876
GO:0009897	External side of plasma membrane	8	0.001475
GO:0005578	Proteinaceous extracellular matrix	7	0.001944
GO:0005576	Extracellular region	13	0.003785
GO:0030018	Z disc	4	0.006991
GO:0030141	Secretory granule	4	0.010644
molecular_function
GO:0048248	CXCR3 chemokine receptor binding	3	3.51E-08
GO:0005525	GTP binding	15	2.48E-07
GO:0003924	GTPase activity	13	3.24E-07
GO:0008009	Chemokine activity	5	1.05E-06
GO:0045236	CXCR chemokine receptor binding	3	3.30E-06
GO:0042288	MHC class I protein binding	3	6.49E-05
GO:0003779	Actin binding	9	9.09E-05
GO:0005506	Iron ion binding	7	0.00032
GO:0004867	Serine-type endopeptidase inhibitor activity	5	0.000333
GO:0051879	Hsp90 protein binding	3	0.000451