Ficus pandurata Hance Inhibits Ulcerative Colitis and Colitis-Associated Secondary Liver Damage of Mice by Enhancing Antioxidation Activity

Figure 3

FPH suppresses DSS-induced colitis in mice by inhibiting the TLR4/MyD88/NF-κB signaling pathway. (a) Histological analysis for the colon by H&E staining (EC: epithelial cell; IG: intestinal glands; SL: submucous layer; ML: muscular layer; McL: mucous layer; GC: goblet cell). The protein expressions of TLR4, MyD88, NF-κB, and phospho-NF-κB in colonic tissues were determined by Western blot (b) and quantitative analysis for Western blot results by normalizing to β-actin (c). (d) The protein expression levels of TLR4 and NF-κB in colonic tissues were detected by IHC. The black arrows were showing the positive cells. Results were expressed as . , vs. the control group; ^#, ^## vs. the model group (DSS only).

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