Research Article
Ficus pandurata Hance Inhibits Ulcerative Colitis and Colitis-Associated Secondary Liver Damage of Mice by Enhancing Antioxidation Activity
Figure 7
FPH alleviates secondary liver injury in colitis mice via suppressing inflammation and the LPS/LBP/CD14/TLR4/NF-κB signaling axis. Effect of FPH on the levels of TNFα (a), LPS (b), LBP (c), sCD14 (d), and IL-18 (e) in the liver tissues of UC mice determined by ELISA. The protein expressions of LBP, CD14, NLRP3, TNFα, TLR4, MyD88, NF-κB, and p-NF-κB in the liver tissues were evaluated by Western blot (f) and quantitative analysis for Western blot results by normalizing to β-actin (g). (h) The protein expression of NLRP3 in the liver tissues of UC mice was detected by IHC. Results were expressed as . , vs. the control group; #, ## vs. the model group (DSS only).
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |
(h) |