Research Article
Pharmacological Activation of Nrf2 by Rosolic Acid Attenuates Endoplasmic Reticulum Stress in Endothelial Cells
Figure 1
Effect of Rosolic acid on ER stress-induced toxicity in EA.hy926 cells. (a) Cytotoxicity of Rosolic acid on EA.hy926 cells as assessed by MTT assay. (b) Cytoprotective effect of Rosolic acid on EA.hy926 cells against thapsigargin-induced toxicity as assessed by MTT assay. Data are represented as of three independent experiments. Significant compared with the control group; determined by one-way ANOVA followed by Tukey’s post hoc test (0, control; TPG, thapsigargin; 2.5, 5, 10, and 25, concentrations of Rosolic acid in μM).
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