[Retracted] Styrylchromones: Biological Activities and Structure-Activity Relationship

Table 2

2-SC studied for the antioxidant activity and summary of the observed antioxidant effects. The table display the antioxidant activity shown for the studied 2-SC according to the criterion: activity greater or equal to 30%.

2-SC	Observed effect(s)	Ref.
3	Scavenging of DPPH^•	[32]
5	Inhibition of XO and high oxidation potential	[22, 27]
11	Inhibition of XO; protective activity against t-BHP-induced hepatotoxicity in rat hepatocytes; scavenging effect against ROS and RNS (O2^•−; H2O2; HOCl; ^1O2; ROO^• and ONOO^−); and moderate oxidation potential	[22, 24, 26, 27]
13	Inhibition of XO; scavenging effect against ROS (O2^•− and HOCl); and high oxidation potential	[22, 26, 27]
14	Inhibition of XO; scavenging effect against ROS and RNS (HOCl; ^1O2; ROO^•; ONOO^− and ^•NO); and high oxidation potential
15	Inhibition of XO; protective activity against t-BHP-induced hepatotoxicity in rat hepatocytes; scavenging effect against ROS and RNS (H2O2 and ONOO^−); and moderate oxidation potential	[22, 24, 26, 27]
16	Inhibition of XO; protective activity against t-BHP-induced hepatotoxicity in rat hepatocytes; scavenging effect against ROS and RNS (O2^•−; HOCl; ^1O2; ROO^• and ONOO^−); and moderate oxidation potential
17 - 19	Inhibition of XO; protective activity against t-BHP-induced hepatotoxicity in rat hepatocytes; inhibition of Cu^2+-induced oxidation of isolated human serum LDL; scavenging effect against ROS and RNS (O2^•−; H2O2; HOCl; ^1O2; ROO^•; ONOO^− and ^•NO); and low oxidation potential	[22, 24–27]
20	Inhibition of Cu^2+-induced oxidation of isolated human serum LDL; scavenging effect against ROS and RNS (O2^•−; H2O2; HOCl; ^1O2; ROO^•; ONOO^− and ^•NO); and low oxidation potential	[25–27]
21	Scavenging effect against ROS and RNS (O2^•−; HOCl; ^1O2; ROO^•; ONOO^− and ^•NO); and moderate oxidation potential	[26, 27]
22 - 24	Scavenging effect against ROS and RNS (O2^•−; H2O2; HOCl; ^1O2; ROO^•; ONOO^− and ^•NO); metal chelating capacity; and reducing activity	[28]
25	Scavenging effect against ROS and RNS (O2^•−; HOCl; ^1O2; ROO^•; ONOO^−, without NaHCO3, and ^•NO)	[29]
26, 27	Scavenging effect against ROS and RNS (O2^•−; HOCl; ^1O2; ROO^•; ONOO^− and ^•NO)
28 - 32	Scavenging of O2^•−	[30]
33	Inhibition of reactive species-induced oxidation of DCFH-DA	[32]

¹O₂: singlet oxygen; t-BHP: tert-butyl hydroperoxide; DCFH-DA: 2,7-dichlorodihydrofluorescein diacetate; DPPH^•: 2,2-Diphenyl-1-picrylhydrazyl radical; H₂O₂: hydrogen peroxide; HOCl: hypochlorous acid; LDL: low-density lipoproteins; ^•NO: nitric oxide radical; ONOO⁻: peroxynitrite anion; RNS: reactive nitrogen species; ROS: reactive oxygen species; ROO^•: peroxyl radical; O₂^•−: superoxide anion radical; XO: xanthine oxidase.