Research Article

ELK1 Promotes Epithelial-Mesenchymal Transition and the Progression of Lung Adenocarcinoma by Upregulating B7-H3

Table 1

ELK1 expression and clinicopathological characteristics of patients with LUAD.

FeaturesELK1 expression value
LowHigh
904149

Age (years)0.0450.832
 ≥604520 (48.8)25 (51.0)
 <604521 (51.2)24 (49.0)
Gender1.9940.158
 Male4919 (46.3)30 (61.2)
 Female4122 (53.7)19 (38.8)
Smoking0.2310.631
 Yes4623 (56.1)25 (51.0)
 No4418 (43.9)24 (49.0)
Differentiation0.6370.425
 Well/moderate3715 (36.6)22 (44.9)
 Poor5326 (63.4)27 (55.1)
Tumor size0.1100.740
 ≤3cm4019 (46.3)21 (42.9)
 >3cm5022 (53.7)28 (57.1)
Lymph node metastasis9.5450.002
 Yes5116 (39.0)35 (71.4)
 No3925 (61.0)14 (28.6)
TNM stage5.4430.020
 I-II5430 (73.2)24 (49.0)
 III-IV3611 (26.8)25 (51.0)