RSL3 Drives Ferroptosis through NF-κB Pathway Activation and GPX4 Depletion in Glioblastoma

Figure 3

NF-κB pathway activation was not mediated by IL-1β release or GPX4 depletion. (a, b) Western blot analysis of NF-κB pathway-related proteins and mature IL-1β expression in U87 and U251 cells. (c) Total and phosphorylated p65 expression after GPX4 knockdown. U87 and U251 cells were treated with 0.25 μM and 0.5 μM RSL3 for 24 h, respectively. Experiments were repeated thrice.

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