Research Article

Oxidized LDL Is Associated with eGFR Decline in Proteinuric Diabetic Kidney Disease: A Cohort Study

Table 2

Cox proportional hazard analysis (forward stepwise regression) showing predictors for the combined end-point in DKD patients.

All-cause mortality or reduction of or progression to ESKD
HR95% CI

Model 1
1.233.421.55-7.560.002
Model 2
1.052.871.14-7.200.025
Baseline eGFR-0.0260.980.96-0.990.013

EGFR: estimated glomerular filtration rate; ESKD: end-stage kidney disease; HR: hazard ratio, CI: confidence interval; Ox-LDL: oxidized low-density lipoprotein; UPCR: urinary protein to creatinine ratio. Model 1: univariate model; model 2: multivariate model adjusted for baseline UPCR and eGFR, serum albumin, and triglycerides.