Research Article

Oxidized LDL Is Associated with eGFR Decline in Proteinuric Diabetic Kidney Disease: A Cohort Study

Table 3

Anthropometric, clinical, and biochemical data of patients with diabetic kidney disease, according to eGFR decline. Results for continuous variables are presented as mean (S.D.) or median (range).

Slow decliners (n=39)Fast decliners ()

History of CV disease (yes)23/3932/390.023
Duration of T2DM (years)12 (7-28)16 (7-34)0.028
Triglycerides (mg/dl)112 (52-320)164 (53-450)0.004
Ox-LDL (U/L)59.5 (22.9-96.5)75.3 (33.2-123.4)0.005
UPCR (g/g)0.12 (0.01-1.5)0.14 (0.01-6.0)0.013

values of independent -test and Mann–Whitney test for differences of variables and χ2 test for differences in frequencies among groups. T2DM: type 2 diabetes mellitus; Ox-LDL: oxidized low-density lipoprotein; eGFR: estimated glomerular filtration rate; UPCR: urinary protein to creatinine ratio.