Research Article
Exosomes Released from CaSR-Stimulated PMNs Reduce Ischaemia/Reperfusion Injury
Figure 9
CaSR-stimulated PMNs protect the myocardium. (a) Different layers of myocardial tissue under various treatments. The Evans blue-stained portion (area not at risk; ANAR), the unstained portion (area at risk; AAR), the ischaemic area (red), and the infarct area (white) are expressed as a % of the AAR. (b) Rat peripheral blood was extracted, and the SOD and MDA contents were detected. (c) Comparison of the LVSP, LVDP, + dp/dtmax, −dp/dtmax of rats from different groups. (d) Effect of exosomes on cardiac function by echocardiographic assessment. Data are shown as the ; vs. the sham group, # vs. the AMI group and, △ vs. the I/R group. Data are representative of three independent experiments.
(a) |
(b) |
(c) |
(d) |