Lifestyle-Induced Redox-Sensitive Alterations: Cross-Talk among the RAAS, Antioxidant/Inflammatory Status, and Hypertension

Figure 6

(a) The effects of lifestyle changes on cardiac extracellular signal-regulated kinase 1/2 expression normalized to β-actin (ERK1/2/β-Actin). Results are presented as , –6. (b) Statistical table of the individual effects and interactions of rat strain, diet, and physical exercise on cardiac ERK1/2/β-actin. (c) The effects of lifestyle changes on cardiac phosphorylated extracellular signal-regulated kinase 1/2 expression normalized to β-actin (pERK1/2/β-actin). Results are presented as , –6. (d) Statistical table of the individual effects and interactions of rat strain, diet, and physical exercise on cardiac pERK1/2/β-actin. (e) Representative Western blot images of the cardiac expressions of ERK1/2, pERK1/2, and β-actin. and : statistical significance relative to the WKY/CTRL group; , , and : statistical significance relative to the SHRSP/CTRL group; ^###: statistical significance between the matching running and nonrunning groups.

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