Research Article

[Retracted] Ginsenoside Rg3 Alleviates Antithyroid Cancer Drug Vandetanib-Induced QT Interval Prolongation

Figure 9

Effect of Rg3 on vandetanib-induced inhibition on steady-state inactivation process of hERG K+ channels in HEK293 cells. (a) hERG channel current steady-state inactivation curve. The steady-state inactivation current diagram of different groups of hERG channels including control (A), vandetanib 2 μM (B), and vandetanib 2 μM with Gin Rg3 3 μM (C). hERG channel current steady-state inactivation fit curve (D). (b) The curves of inactivation time constants of control (A), vandetanib 2 μM (B), and vandetanib 2 μM with Gin Rg3 3 μM (C). (D) The statistics of inactivation time constant. Data are represented by the . Compared with control, and .
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