The Potential Effects of Oxidative Stress-Related Plasma Abnormal Protein Aggregate Levels on Brain Volume and Its Neuropsychiatric Consequences in Parkinson’s Disease

Table 2

Regions showing gray matter volume differences between PD patients with normal cognition (PDN) and cognitive decline (PDCD).

MNI atlas coordinates			Voxel size	Gray matter	BA	GMV (mm^3)
X	Y	Z				PDN	PDCD
-32	-12	-11	753	Putamen, L	—			4.18
14	-7	-26	108	Hippocampal complex, R	34			3.56
27	12	3	388	Putamen, R	—			3.47
57	-12	16	187	Superior temporal gyrus, R	41			3.43
12	-25	43	178	Cingulate gyrus, R	31			3.2
50	12	-38	187	Middle temporal gyrus, R	38			3.16

Abbreviations: MNI: Montreal Neurological Institute; BA: Brodmann area; GMV: gray matter volume; R: right side; L: left side. The statistical criteria were set at joint voxel height uncorrected and voxel size >100.