Research Article

The Leaf Extract of Coccinia grandis (L.) Voigt Accelerated In Vitro Wound Healing by Reducing Oxidative Stress Injury

Figure 2

The graphs showed the viability of human keratinocyte, HaCaT, and human fibroblast, HFb, cell lines upon (a) hydrogen peroxide (H2O2) treatment and (b) the leaf extract treatment. The capability of the leaf extracts to rescue the hydrogen peroxide-induced oxidative stress and cytotoxicity was employed in (c) HaCaT cell line and (d) HFb cell line. The data were analyzed with one-way ANOVA with Dunnett post hoc analysis, . , , and compared to hydrogen peroxide-treated condition (+H2O2). Besides, the treatment of 200 μg/mL methanol leaf extract following hydrogen peroxide-induced oxidative stress and cytotoxicity was not significantly different (shown as “ns”) compared with no hydrogen peroxide induction (-H2O2).
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