Associations among Cognitive Functions, Plasma DNA, and Diffusion Tensor Image along the Perivascular Space (DTI-ALPS) in Patients with Parkinson’s Disease

Table 1

Demographic characteristics of the PD patients and normal controls.

	Normal group	Patients with PD ()			value
	()	PDN ()	PD-MCI ()	PDD ()
Sex (male, female)	15, 32	15, 10	8, 17	11, 27	0.056
Age (years)					0.034	¶
Disease duration (years)	—				0.333
UPDRS I	—				0.886
UPDRS II	—				0.262
UPDRS III	—				0.157
UPDRS total	—				0.213
Modified HY stage	—				0.418
SE-ADL	—				0.731
CASI					<0.001	¶&†
MMSE					<0.001	¶&†
Plasma DNA
Nuclear DNA (ng/mL)					<0.001	¶&†
Mitochondrial DNA (ng/mL)					0.206

Data are presented as . The age data were compared by analysis of variance (ANOVA). Sex data were compared by Pearson chi-squared test. Clinical severity score and plasma DNA data were compared by analysis of covariance (ANCOVA) after controlling for age and sex with Bonferroni correction. value represented the comparison amounts of the PDN, PD-MCI, and PDD patients and the normal control group. Significant differences among groups; ¶Significant differences between NC and PDD; &Significant differences between PDN and PDD; †Significant differences between PD-MCI and PDD.