Oxidative Medicine and Cellular Longevity / 2021 / Article / Fig 3

Research Article

Exogenous and Endogenous Serine Deficiency Exacerbates Hepatic Lipid Accumulation

Figure 3

Serine deficiency aggravated oxidative and inflammatory status in liver. GSH: glutathione. Relative mRNA expression of IL-1β (a), TNF-α (b), and IL-6 (c). (d) GSH content in the liver. (e) ROS content (red) in the liver. (f) Relative fluorescence of ROS staining. CONT: mice were fed on the control diet; NS: mice were fed on the serine- and glycine-deficient diet; NCT: mice were fed on the control diet and supplemented with NCT-503. Data are presented as . for the mRNA expression and GSH content and for ROS staining. a,bMeans of the bars with different letters were significantly different among groups ().
(a)
(b)
(c)
(d)
(e)
(f)

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.