Exogenous and Endogenous Serine Deficiency Exacerbates Hepatic Lipid Accumulation

<div>Dietary NCT-503 supplementation decreased serine content in liver. PHGDH: phosphoglycerate dehydrogenase; PAST1: phosphoserine aminotransferase; PSPH: phosphoserine phosphatase. Serine content in serum (a) and liver (b). (c) PHGDH activity. Relative mRNA expression of <i>PAST1</i> (d) and <i>PSPH</i> (e). CONT: mice were fed on the control diet; NS: mice were fed on the serine-and glycine-deficient diet; NCT: mice were fed on the control diet and supplemented with NCT-503. 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Oxidative Medicine and Cellular Longevity

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Figure 4

Figure 4: Exogenous and Endogenous Serine Deficiency Exacerbates Hepatic Lipid Accumulation 