Controlled Decompression Attenuates Compressive Injury following Traumatic Brain Injury via TREK-1-Mediated Inhibition of Necroptosis and Neuroinflammation

<div>CDC attenuates brain damage after traumatic intracranial hypertension. (a) The horizontal and coronal schematic diagrams of the traumatic intracranial hypertension model. (b) Brain water content assay shows that CDC for 20 min or 30 min reduced brain edema compared to RDC. (c) The neurological assay shows that CDC for 20 min or 30 min attenuates locomotor impairment compared to RDC. (d, e) Typical pictures of NeuN staining (d) and quantification (e) show that CDC for 20 min or 30 min decreases neuronal loss compared to RDC. 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Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: Controlled Decompression Attenuates Compressive Injury following Traumatic Brain Injury via TREK-1-Mediated Inhibition of Necroptosis and Neuroinflammation 

Figure 1 | Controlled Decompression Attenuates Compressive Injury following Traumatic Brain Injury via TREK-1-Mediated Inhibition of Necroptosis and Neuroinflammation 