Research Article
Controlled Decompression Attenuates Compressive Injury following Traumatic Brain Injury via TREK-1-Mediated Inhibition of Necroptosis and Neuroinflammation
Figure 11
Involvement of TREK-1 in CDC-induced protection. (a) The CDC-induced decrease in LDH release was prevented by spadin and SID1900. (b) The CDC-induced increase in calcein signal was prevented by spadin and SID1900. (c) The CDC-induced inhibition of RIP3 activation was prevented by spadin and SID1900. (d) The CDC-induced inhibition of neuronal necrosis was prevented by spadin, but not by SID1900. The data was represented as . # vs. control group, vs. TNI+compression group, and & vs. CDC+TNI+compression group.
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