Controlled Decompression Attenuates Compressive Injury following Traumatic Brain Injury via TREK-1-Mediated Inhibition of Necroptosis and Neuroinflammation

<div>CDC alleviates neuronal necroptosis and neuroinflammation. (a, b) Typical pictures of RIP1 staining (a) and quantification (b) show that CDC had no effect on the RDC-induced increase of RIP1 expression. The scale bar is 50 <i>μ</i>m. (c, d) Typical pictures of RIP3 staining (c) and quantification (d) show that CDC attenuates the RIP3 expression compared to RDC. The scale bar is 50 <i>μ</i>m. (e, f) Typical pictures of CD68 staining (e) and quantification (f) show that CDC attenuates microglial activation compared to RDC. The scale bar is 50 <i>μ</i>m. 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Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Controlled Decompression Attenuates Compressive Injury following Traumatic Brain Injury via TREK-1-Mediated Inhibition of Necroptosis and Neuroinflammation 

Figure 2 | Controlled Decompression Attenuates Compressive Injury following Traumatic Brain Injury via TREK-1-Mediated Inhibition of Necroptosis and Neuroinflammation 