Research Article
Changes in Hepcidin Levels in an Animal Model of Anemia of Chronic Inflammation: Mechanistic Insights Related to Iron Supplementation and Hepcidin Regulation
Figure 6
Effect of complete Freund’s adjuvant (CFA) and intravenous iron treatment on the hepcidin regulation pathways in the rat liver. The relative protein levels were quantified using densitometry. C: control-saline group (); V: CFA-saline group (); I: CFA-iron group (); STAT-3: signal transducer and activator of transcription-3; P-STAT-3: phosphorylated STAT-3; SMAD: sma mothers against decapentaplegic; P-SMAD: phosphorylated SMAD; GAPDH: glyceraldehyde-3-phosphate dehydrogenase. compared with the control group; compared with the CFA-saline group.
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