Calcium-/Calmodulin-Dependent Protein Kinase II (CaMKII) Inhibition Induces Learning and Memory Impairment and Apoptosis

Figure 7

The p-JNK signaling pathway contributes to KN93-induced apoptosis. (a, b) Apoptosis was observed in the control group, KN93 group, and group of PC12 cells using flow cytometry. , compared with the control group. (c, d) Representative protein bands and analysis of data for caspase-3, Bcl-2, Bax, and cytochrome c in control groups, KN93 groups, and groups of PC12 cells and primary hippocampal neurons. , compared with the control group; , compared with the control group; , compared with the control group; , compared with the KN93 group.

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