Research Article
p53 Inhibition Protects against Neuronal Ischemia/Reperfusion Injury by the p53/PRAS40/mTOR Pathway
Figure 3
Proteins related to Akt/PRAS40/mTOR were examined by western blotting (a) and quantified (b) 48āh after MCAO. The expression of p-Akt, p-PRAS40, p-S6K, and p-mTOR was higher in p53-/- and p53+/- mice than in p53+/+ mice (WT). vs. the WT+MCAO group; # vs. the WT+sham group. ā8/group.
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