Synthesis, Anticancer Assessment, and Molecular Docking of Novel Chalcone-Thienopyrimidine Derivatives in HepG2 and MCF-7 Cell Lines

<div>Effect of six tested compounds (<b>3g</b>, <b>3a</b>, <b>3c</b>, <b>3b</b>, <b>3d</b>, and <b>3e</b>) on cell proliferation and cell cycle phases of HepG2. (a) Change in the cell cycle of untreated (cont.), 5-fluorouracil (5-FU), and treated HepG2 was analyzed using a flow cytometer. (b) The percentage of the cell population in the phases of the HepG2 cell cycle. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Synthesis, Anticancer Assessment, and Molecular Docking of Novel Chalcone-Thienopyrimidine Derivatives in HepG2 and MCF-7 Cell Lines 