Synthesis, Anticancer Assessment, and Molecular Docking of Novel Chalcone-Thienopyrimidine Derivatives in HepG2 and MCF-7 Cell Lines

<div>Evaluation of apoptosis in the MCF-7 cell line treated with the six tested compounds (<b>3b</b> and <b>3g</b>). (a) Apoptosis was analyzed using Annexin V-FITC/PI staining and flow cytometry. The right lower quadrant demonstrates early apoptotic cells, and the right upper quadrant demonstrates late apoptotic cells. (b) The bar graph showed quantification of the percentage of the early and late apoptotic MCF-7 cell line. 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Oxidative Medicine and Cellular Longevity

fig7

Figure 7

Figure 7: Synthesis, Anticancer Assessment, and Molecular Docking of Novel Chalcone-Thienopyrimidine Derivatives in HepG2 and MCF-7 Cell Lines 