Synthesis, Anticancer Assessment, and Molecular Docking of Novel Chalcone-Thienopyrimidine Derivatives in HepG2 and MCF-7 Cell Lines

<div>Effect of newly synthesized chalcone-thienopyrimidine derivatives <b>3a-e</b> and <b>3g</b> (IC<sub>50</sub>) (a) and the newly synthesized chalcone-thienopyrimidine derivatives <b>3b</b> and <b>3g</b> (IC<sub>50</sub>) (b) on the gene expression of Bcl-2, Bax, Bax/Bcl-2 ratio, caspase-3, and caspase-9 in HepG2 (a) and MCF-7 (b) cell lines after 8-hour incubation. 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Oxidative Medicine and Cellular Longevity

fig8

Figure 8

Figure 8: Synthesis, Anticancer Assessment, and Molecular Docking of Novel Chalcone-Thienopyrimidine Derivatives in HepG2 and MCF-7 Cell Lines 