The Relationship between Serum Trace Elements and Oxidative Stress of Patients with Different Types of Cancer

Table 5

Correlation between TEs and OxS parameter in different cancer subgroups.

	TOS		TAS		OSI
	(95% CI)		(95% CI)		(95% CI)
Liver cancer ()
Cu	0.689(0.574, 0.777)	<0.001	-0.739(-0.814. -0.638)	<0.001	0.795(0.713, 0.856)	<0.001
Zn	-0.382(-0.533, -0.207)	<0.001	0.491(0.332, 0.623)	<0.001	-0.458(-0.596, -0.293)	<0.001
Fe	0.270(0.085, 0.437)	0.005	-0.252(-0.422, -0.066)	0.009	0.306(0.123, 0.469)	0.001
Se	0.068(-0.124, 0.254)	0.489	0.138(-0.053, 0.319)	0.157	0.098(-0.094, 0.283)	0.315
Gastric carcinoma ()
Cu	0.619(0.494, 0.719)	<0.001	-0.645(-0.739, -0.526)	<0.001	0.687(0.578, 0.771)	<0.001
Zn	-0.271(-0.430, -0.096)	0.003	0.266(0.091, 0.426)	0.003	-0.314(-0.468, -0.142)	<0.001
Fe	0.043(-0.138, 0.222)	0.640	-0.175(-0.345, 0.005)	0.056	0.099(-0.083, 0.274)	0.286
Se	-0.069(-0.246, 0.113)	0.459	0.117(-0.064, 0.291)	0.205	0.048(-0.133, 0.226)	0.602
Colorectal cancer ()
Cu	0.636(0.515, 0.732)	<0.001	-0.520(-0.640, -0.376)	<0.001	0.632(0.510, 0.728)	<0.001
Zn	-0.316(-0.468, -0.145)	<0.001	0.340(0.171, 0.489)	<0.001	-0.362(-0.508, -0.195)	<0.001
Fe	0.329(0.159, 0.480)	<0.001	-0.347(-0.495, -0.179)	<0.001	0.371(0.205, 0.516)	<0.001
Se	0.013(-0.167, 0.191)	0.892	-0.046(-0.223, 0.135)	0.621	0.041(-0.139, 0.219)	0.655
Breast cancer ()
Cu	0.580(0.452, 0.685)	<0.001	-0.534(-0.648, -0.398)	<0.001	0.627(0.509, 0.722)	<0.001
Zn	-0.259(-0.414, -0.090)	0.003	0.302(0.136, 0.452)	<0.001	-0.353(-0.496, -0.191)	<0.001
Fe	0.239(0.068, 0.396)	0.007	-0.214(-0.374, -0.042)	0.015	0.261(0.092, 0.416)	0.003
Se	-0.202(-0.363, -0.030)	0.022	0.203(0.030, 0.363)	0.022	-0.218(-0.377, -0.046)	0.014
Lung cancer ()
Cu	0.583(0.467, 0.680)	<0.001	-0.519(-0.627, -0.391)	<0.001	0.631(0.523, 0.718)	<0.001
Zn	-0.278(-0.420, -0.124)	<0.001	0.339(0.189, 0.474)	<0.001	-0.342(-0.476, -0.192)	<0.001
Fe	0.674(0.576, 0.753)	<0.001	-0.685(-0.762, -0.590)	<0.001	0.760(0.683, 0.820)	<0.001
Se	-0.261(-0.405, -0.106)	0.001	0.219(0.061, 0.366)	0.007	-0.248(-0.393, -0.091)	0.002
Esophageal cancer ()
Cu	0.657(0.540, 0.749)	<0.001	-0.647(-0.741, -0.527)	<0.001	0.714(0.612, 0.793)	<0.001
Zn	-0.498(-0.623, -0.348)	<0.001	0.491(0.340, 0.618)	<0.001	-0.521(-0.621, -0.396)	<0.001
Fe	0.529(0.385, 0.648)	<0.001	-0.585(-0.693, -0.451)	<0.001	0.644(0.523, 0.739)	<0.001
Se	-0.327(-0.480, -0.154)	<0.001	0.381(0.214, 0.526)	<0.001	-0.408(-0.549, -0.245)	<0.001
Brain cancer ()
Cu	0.479(0.325, 0.609)	<0.001	-0.584(-0.693, -0.448)	<0.001	0.627(0.502, 0.727)	<0.001
Zn	0.145(-0.040, 0.319)	0.123	-0.147(-0.311, 0.025)	0.094	0.182(-0.001, 0.354)	0.051
Fe	0.107(-0.078, 0.284)	0.257	-0.075(-0.254, 0.110)	0.428	0.125(-0.060, 0.301)	0.183
Se	0.111(-0.047, 0.264)	0.167	-0.067(-0.248, 0.117)	0.473	0.142(-0.042, 0.317)	0.130
Kidney cancer ()
Cu	0.342(0.195, 0.474)	<0.001	-0.305(-0.441, -0.155)	<0.001	0.344(0.198, 0.476)	<0.001
Zn	-0.231(-0.374, -0.077)	0.004	0.298(0.148, 0.435)	<0.001	-0.280(-0.419, -0.129)	<0.001
Fe	0.073(-0.085, 0.228)	0.365	-0.098(-0.251, 0.060)	0.224	0.096(-0.063, 0.249)	0.236
Se	-0.187(-0.358, -0.004)	0.045	0.234(0.080, 0.377)	0.003	-0.192(-0.339, -0.036)	0.016
Others ()
Cu	0.365(0.206, 0.505)	<0.001	-0.297(-0.446, -0.132)	<0.001	0.397(0.242, 0.532)	<0.001
Zn	-0.364(-0.504, -0.206)	<0.001	0.200(0.017, 0.369)	0.032	-0.290(-0.440, -0.125)	<0.001
Fe	0.270(0.103, 0.422)	0.002	-0.246(-0.401, -0.078)	0.005	0.298(0.133, 0.447)	<0.001
Se	-0.378(-0.516, -0.221)	<0.001	0.279(0.112, 0.430)	0.001	-0.406(-0.540, -0.252)	<0.001

Note: Spearman correlation analysis is used.