Identification of Sitogluside as a Potential Skin-Pigmentation-Reducing Agent through Network Pharmacology

Figure 5

Sitogluside inhibits TYR activity. (a) The molecular docking between sitogluside, arbutin, nicotinamide, hydroquinone, kojic acid, azelaic acid, ascorbic acid, and tyrosinase. (b, c) The tyrosinase activity assay detects the TYR activity of MNT1 and B16F0 after treatment with different concentrations of sitogluside. (d) A near-infrared fluorescence probe was used to detect the TYR activity in MNT1.

(a)

(b)

(c)

(d)