Targeting Mitochondrial Biogenesis with Polyphenol Compounds

Figure 3

Alteration in ultrastructural and mass of adipocyte mitochondria induced by hydroxytyrosol treatments (1.0 μM for 48 h). (a) Upsurge in the fluorescence intensity in MitoTracker staining. (b) Significant change () in mitochondrial surface area and density in morphometric analysis using electron microscopy. (c) Electron microscope comparison of mitochondrial profiles (A, B) (magnification ×2110) and (C, D) (magnification ×11,000). Reproduced with permission of Elsevier [83].

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