Ginsenoside Rg5 Inhibits Human Osteosarcoma Cell Proliferation and Induces Cell Apoptosis through PI3K/Akt/mTORC1-Related LC3 Autophagy Pathway

Figure 4

Silencing LC3 affects Rg5-induced tumor cell apoptosis. LC3 protein and gene expression were detected by western blot (a, b) and qRT-PCR experiments (c) when the LC3 expression was silenced by RNAi in MG-63 cells. (d, e) The MFI of LC3 in MG-63 cells detected by FACS. (f) MG-63 cell apoptosis detected by FACS. The data are shown as (, ^ns, vs. control).

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